Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice.
Identifieur interne : 000515 ( Main/Exploration ); précédent : 000514; suivant : 000516Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice.
Auteurs : Tim Spelman [Australie] ; Claire Meyniel [Australie] ; Juan Ignacio Rojas [Argentine] ; Alessandra Lugaresi [Italie] ; Guillermo Izquierdo [Espagne] ; Francois Grand'Maison [Canada] ; Cavit Boz [Turquie] ; Raed Alroughani [Koweït] ; Eva Havrdova [République tchèque] ; Dana Horakova [République tchèque] ; Gerardo Iuliano [Italie] ; Pierre Duquette [Canada] ; Murat Terzi [Turquie] ; Pierre Grammond [Canada] ; Raymond Hupperts [Pays-Bas] ; Jeannette Lechner-Scott [Australie] ; Celia Oreja-Guevara [Espagne] ; Eugenio Pucci [Italie] ; Freek Verheul [Pays-Bas] ; Marcela Fiol [Argentine] ; Vincent Van Pesch [Belgique] ; Edgardo Cristiano [Argentine] ; Thor Petersen [Danemark] ; Fraser Moore [Canada] ; Tomas Kalincik [Australie] ; Vilija Jokubaitis [Australie] ; Maria Trojano [Italie] ; Helmut Butzkueven [Australie]Source :
- Multiple sclerosis (Houndmills, Basingstoke, England) [ 1477-0970 ] ; 2017.
Abstract
Characteristics at clinically isolated syndrome (CIS) examination assist in identification of patient at highest risk of early second attack and could benefit the most from early disease-modifying drugs (DMDs).
DOI: 10.1177/1352458516679893
PubMed: 27885062
Affiliations:
- Argentine, Australie, Belgique, Canada, Danemark, Espagne, Italie, Koweït, Pays-Bas, République tchèque, Turquie
- Bohême centrale, Communauté de Madrid, Région de Bruxelles-Capitale, Victoria (État)
- Bruxelles, Madrid, Melbourne, Prague
- Université de Melbourne
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Trabzon</wicri:regionArea><wicri:noRegion>Trabzon</wicri:noRegion></affiliation></author><author><name sortKey="Alroughani, Raed" sort="Alroughani, Raed" uniqKey="Alroughani R" first="Raed" last="Alroughani">Raed Alroughani</name><affiliation wicri:level="1"><nlm:affiliation>Amiri Hospital, Kuwait City, Kuwait.</nlm:affiliation><country xml:lang="fr">Koweït</country><wicri:regionArea>Amiri Hospital, Kuwait City</wicri:regionArea><wicri:noRegion>Kuwait City</wicri:noRegion></affiliation></author><author><name sortKey="Havrdova, Eva" sort="Havrdova, Eva" uniqKey="Havrdova E" first="Eva" last="Havrdova">Eva Havrdova</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital and Charles University in Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Neurology and Center of Clinical Neuroscience, First 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centrale</region></placeName></affiliation></author><author><name sortKey="Iuliano, Gerardo" sort="Iuliano, Gerardo" uniqKey="Iuliano G" first="Gerardo" last="Iuliano">Gerardo Iuliano</name><affiliation wicri:level="1"><nlm:affiliation>Ospedali Riuniti di Salerno, Salerno, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Ospedali Riuniti di Salerno, Salerno</wicri:regionArea><wicri:noRegion>Salerno</wicri:noRegion></affiliation></author><author><name sortKey="Duquette, Pierre" sort="Duquette, Pierre" uniqKey="Duquette P" first="Pierre" last="Duquette">Pierre Duquette</name><affiliation wicri:level="1"><nlm:affiliation>Hôpital Notre-Dame, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Hôpital Notre-Dame, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Terzi, Murat" sort="Terzi, Murat" uniqKey="Terzi M" first="Murat" last="Terzi">Murat Terzi</name><affiliation wicri:level="1"><nlm:affiliation>Ondokuz Mayis University, Samsun, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Ondokuz Mayis University, Samsun</wicri:regionArea><wicri:noRegion>Samsun</wicri:noRegion></affiliation></author><author><name sortKey="Grammond, Pierre" sort="Grammond, Pierre" uniqKey="Grammond P" first="Pierre" last="Grammond">Pierre Grammond</name><affiliation wicri:level="1"><nlm:affiliation>Centre de réadaptation en déficience physique Chaudière-Appalaches, Levis, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de réadaptation en déficience physique Chaudière-Appalaches, Levis, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Hupperts, Raymond" sort="Hupperts, Raymond" uniqKey="Hupperts R" first="Raymond" last="Hupperts">Raymond Hupperts</name><affiliation wicri:level="1"><nlm:affiliation>Maaslandziekenhuis, Sittard, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Maaslandziekenhuis, Sittard</wicri:regionArea><wicri:noRegion>Sittard</wicri:noRegion></affiliation></author><author><name sortKey="Lechner Scott, Jeannette" sort="Lechner Scott, Jeannette" uniqKey="Lechner Scott J" first="Jeannette" last="Lechner-Scott">Jeannette Lechner-Scott</name><affiliation wicri:level="1"><nlm:affiliation>John Hunter Hospital, Newcastle, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>John Hunter Hospital, Newcastle, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Oreja Guevara, Celia" sort="Oreja Guevara, Celia" uniqKey="Oreja Guevara C" first="Celia" last="Oreja-Guevara">Celia Oreja-Guevara</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Clínico San Carlos, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Clínico San Carlos, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Pucci, Eugenio" sort="Pucci, Eugenio" uniqKey="Pucci E" first="Eugenio" last="Pucci">Eugenio Pucci</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Unit, ASUR Marche - AV3, Macerata, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology Unit, ASUR Marche - AV3, Macerata</wicri:regionArea><wicri:noRegion>Macerata</wicri:noRegion></affiliation></author><author><name sortKey="Verheul, Freek" sort="Verheul, Freek" uniqKey="Verheul F" first="Freek" last="Verheul">Freek Verheul</name><affiliation wicri:level="1"><nlm:affiliation>Groene Hart Ziekenhuis, Gouda, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Groene Hart Ziekenhuis, Gouda</wicri:regionArea><wicri:noRegion>Gouda</wicri:noRegion></affiliation></author><author><name sortKey="Fiol, Marcela" sort="Fiol, Marcela" uniqKey="Fiol M" first="Marcela" last="Fiol">Marcela Fiol</name><affiliation wicri:level="1"><nlm:affiliation>Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Van Pesch, Vincent" sort="Van Pesch, Vincent" uniqKey="Van Pesch V" first="Vincent" last="Van Pesch">Vincent Van Pesch</name><affiliation wicri:level="3"><nlm:affiliation>Cliniques Universitaires Saint-Luc, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Cliniques Universitaires Saint-Luc, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Cristiano, Edgardo" sort="Cristiano, Edgardo" uniqKey="Cristiano E" first="Edgardo" last="Cristiano">Edgardo Cristiano</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Italiano de Buenos Aires, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, Thor" sort="Petersen, Thor" uniqKey="Petersen T" first="Thor" last="Petersen">Thor Petersen</name><affiliation wicri:level="1"><nlm:affiliation>Kommunehospitalet, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Kommunehospitalet, 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sortKey="Trojano, Maria" sort="Trojano, Maria" uniqKey="Trojano M" first="Maria" last="Trojano">Maria Trojano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Bari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Bari</wicri:regionArea><wicri:noRegion>Bari</wicri:noRegion></affiliation></author><author><name sortKey="Butzkueven, Helmut" sort="Butzkueven, Helmut" uniqKey="Butzkueven H" first="Helmut" last="Butzkueven">Helmut Butzkueven</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Box Hill hospital, Monash University, Box Hill, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Box Hill hospital, Monash University, Box Hill, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27885062</idno><idno type="pmid">27885062</idno><idno type="doi">10.1177/1352458516679893</idno><idno type="wicri:Area/PubMed/Corpus">000669</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000669</idno><idno type="wicri:Area/PubMed/Curation">000667</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000667</idno><idno type="wicri:Area/PubMed/Checkpoint">000667</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000667</idno><idno type="wicri:Area/Ncbi/Merge">003F30</idno><idno type="wicri:Area/Ncbi/Curation">003F30</idno><idno type="wicri:Area/Ncbi/Checkpoint">003F30</idno><idno type="wicri:Area/Main/Merge">000510</idno><idno type="wicri:Area/Main/Curation">000515</idno><idno type="wicri:Area/Main/Exploration">000515</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice.</title><author><name sortKey="Spelman, Tim" sort="Spelman, Tim" uniqKey="Spelman T" first="Tim" last="Spelman">Tim Spelman</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Meyniel, Claire" sort="Meyniel, Claire" uniqKey="Meyniel C" first="Claire" last="Meyniel">Claire Meyniel</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Rojas, Juan Ignacio" sort="Rojas, Juan Ignacio" uniqKey="Rojas J" first="Juan Ignacio" last="Rojas">Juan Ignacio Rojas</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Italiano de Buenos Aires, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Lugaresi, Alessandra" sort="Lugaresi, Alessandra" uniqKey="Lugaresi A" first="Alessandra" last="Lugaresi">Alessandra Lugaresi</name><affiliation wicri:level="1"><nlm:affiliation>MS Center, Department of Neuroscience and Imaging, University 'G. d'Annunzio', Chieti, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>MS Center, Department of Neuroscience and Imaging, University 'G. d'Annunzio', Chieti</wicri:regionArea><wicri:noRegion>Chieti</wicri:noRegion></affiliation></author><author><name sortKey="Izquierdo, Guillermo" sort="Izquierdo, Guillermo" uniqKey="Izquierdo G" first="Guillermo" last="Izquierdo">Guillermo Izquierdo</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Universitario Virgen Macarena, Sevilla, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Universitario Virgen Macarena, Sevilla</wicri:regionArea><wicri:noRegion>Sevilla</wicri:noRegion></affiliation></author><author><name sortKey="Grand Maison, Francois" sort="Grand Maison, Francois" uniqKey="Grand Maison F" first="Francois" last="Grand'Maison">Francois Grand'Maison</name><affiliation wicri:level="1"><nlm:affiliation>Neuro Rive-Sud, Hôpital Charles LeMoyne, Greenfield Park, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Neuro Rive-Sud, Hôpital Charles LeMoyne, Greenfield Park, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Boz, Cavit" sort="Boz, Cavit" uniqKey="Boz C" first="Cavit" last="Boz">Cavit Boz</name><affiliation wicri:level="1"><nlm:affiliation>Karadeniz Technical University, Trabzon, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Karadeniz Technical University, Trabzon</wicri:regionArea><wicri:noRegion>Trabzon</wicri:noRegion></affiliation></author><author><name sortKey="Alroughani, Raed" sort="Alroughani, Raed" uniqKey="Alroughani R" first="Raed" last="Alroughani">Raed Alroughani</name><affiliation wicri:level="1"><nlm:affiliation>Amiri Hospital, Kuwait City, Kuwait.</nlm:affiliation><country xml:lang="fr">Koweït</country><wicri:regionArea>Amiri Hospital, Kuwait City</wicri:regionArea><wicri:noRegion>Kuwait City</wicri:noRegion></affiliation></author><author><name sortKey="Havrdova, Eva" sort="Havrdova, Eva" uniqKey="Havrdova E" first="Eva" last="Havrdova">Eva Havrdova</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital and Charles University in Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital and Charles University in Prague, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Horakova, Dana" sort="Horakova, Dana" uniqKey="Horakova D" first="Dana" last="Horakova">Dana Horakova</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital and Charles University in Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital and Charles University in Prague, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Iuliano, Gerardo" sort="Iuliano, Gerardo" uniqKey="Iuliano G" first="Gerardo" last="Iuliano">Gerardo Iuliano</name><affiliation wicri:level="1"><nlm:affiliation>Ospedali Riuniti di Salerno, Salerno, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Ospedali Riuniti di Salerno, Salerno</wicri:regionArea><wicri:noRegion>Salerno</wicri:noRegion></affiliation></author><author><name sortKey="Duquette, Pierre" sort="Duquette, Pierre" uniqKey="Duquette P" first="Pierre" last="Duquette">Pierre Duquette</name><affiliation wicri:level="1"><nlm:affiliation>Hôpital Notre-Dame, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Hôpital Notre-Dame, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Terzi, Murat" sort="Terzi, Murat" uniqKey="Terzi M" first="Murat" last="Terzi">Murat Terzi</name><affiliation wicri:level="1"><nlm:affiliation>Ondokuz Mayis University, Samsun, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Ondokuz Mayis University, Samsun</wicri:regionArea><wicri:noRegion>Samsun</wicri:noRegion></affiliation></author><author><name sortKey="Grammond, Pierre" sort="Grammond, Pierre" uniqKey="Grammond P" first="Pierre" last="Grammond">Pierre Grammond</name><affiliation wicri:level="1"><nlm:affiliation>Centre de réadaptation en déficience physique Chaudière-Appalaches, Levis, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de réadaptation en déficience physique Chaudière-Appalaches, Levis, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Hupperts, Raymond" sort="Hupperts, Raymond" uniqKey="Hupperts R" first="Raymond" last="Hupperts">Raymond Hupperts</name><affiliation wicri:level="1"><nlm:affiliation>Maaslandziekenhuis, Sittard, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Maaslandziekenhuis, Sittard</wicri:regionArea><wicri:noRegion>Sittard</wicri:noRegion></affiliation></author><author><name sortKey="Lechner Scott, Jeannette" sort="Lechner Scott, Jeannette" uniqKey="Lechner Scott J" first="Jeannette" last="Lechner-Scott">Jeannette Lechner-Scott</name><affiliation wicri:level="1"><nlm:affiliation>John Hunter Hospital, Newcastle, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>John Hunter Hospital, Newcastle, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Oreja Guevara, Celia" sort="Oreja Guevara, Celia" uniqKey="Oreja Guevara C" first="Celia" last="Oreja-Guevara">Celia Oreja-Guevara</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Clínico San Carlos, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Clínico San Carlos, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Pucci, Eugenio" sort="Pucci, Eugenio" uniqKey="Pucci E" first="Eugenio" last="Pucci">Eugenio Pucci</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Unit, ASUR Marche - AV3, Macerata, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology Unit, ASUR Marche - AV3, Macerata</wicri:regionArea><wicri:noRegion>Macerata</wicri:noRegion></affiliation></author><author><name sortKey="Verheul, Freek" sort="Verheul, Freek" uniqKey="Verheul F" first="Freek" last="Verheul">Freek Verheul</name><affiliation wicri:level="1"><nlm:affiliation>Groene Hart Ziekenhuis, Gouda, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Groene Hart Ziekenhuis, Gouda</wicri:regionArea><wicri:noRegion>Gouda</wicri:noRegion></affiliation></author><author><name sortKey="Fiol, Marcela" sort="Fiol, Marcela" uniqKey="Fiol M" first="Marcela" last="Fiol">Marcela Fiol</name><affiliation wicri:level="1"><nlm:affiliation>Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Van Pesch, Vincent" sort="Van Pesch, Vincent" uniqKey="Van Pesch V" first="Vincent" last="Van Pesch">Vincent Van Pesch</name><affiliation wicri:level="3"><nlm:affiliation>Cliniques Universitaires Saint-Luc, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Cliniques Universitaires Saint-Luc, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Cristiano, Edgardo" sort="Cristiano, Edgardo" uniqKey="Cristiano E" first="Edgardo" last="Cristiano">Edgardo Cristiano</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Italiano de Buenos Aires, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, Thor" sort="Petersen, Thor" uniqKey="Petersen T" first="Thor" last="Petersen">Thor Petersen</name><affiliation wicri:level="1"><nlm:affiliation>Kommunehospitalet, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Kommunehospitalet, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Moore, Fraser" sort="Moore, Fraser" uniqKey="Moore F" first="Fraser" last="Moore">Fraser Moore</name><affiliation wicri:level="1"><nlm:affiliation>Jewish General Hospital, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Jewish General Hospital, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Kalincik, Tomas" sort="Kalincik, Tomas" uniqKey="Kalincik T" first="Tomas" last="Kalincik">Tomas Kalincik</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Jokubaitis, Vilija" sort="Jokubaitis, Vilija" uniqKey="Jokubaitis V" first="Vilija" last="Jokubaitis">Vilija Jokubaitis</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Trojano, Maria" sort="Trojano, Maria" uniqKey="Trojano M" first="Maria" last="Trojano">Maria Trojano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Bari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Bari</wicri:regionArea><wicri:noRegion>Bari</wicri:noRegion></affiliation></author><author><name sortKey="Butzkueven, Helmut" sort="Butzkueven, Helmut" uniqKey="Butzkueven H" first="Helmut" last="Butzkueven">Helmut Butzkueven</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Box Hill hospital, Monash University, Box Hill, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Box Hill hospital, Monash University, Box Hill, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author></analytic><series><title level="j">Multiple sclerosis (Houndmills, Basingstoke, England)</title><idno type="eISSN">1477-0970</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Characteristics at clinically isolated syndrome (CIS) examination assist in identification of patient at highest risk of early second attack and could benefit the most from early disease-modifying drugs (DMDs).</div></front></TEI><affiliations><list><country><li>Argentine</li><li>Australie</li><li>Belgique</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>Italie</li><li>Koweït</li><li>Pays-Bas</li><li>République tchèque</li><li>Turquie</li></country><region><li>Bohême centrale</li><li>Communauté de Madrid</li><li>Région de Bruxelles-Capitale</li><li>Victoria (État)</li></region><settlement><li>Bruxelles</li><li>Madrid</li><li>Melbourne</li><li>Prague</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><country name="Australie"><region name="Victoria (État)"><name sortKey="Spelman, Tim" sort="Spelman, Tim" uniqKey="Spelman T" first="Tim" last="Spelman">Tim Spelman</name></region><name sortKey="Butzkueven, Helmut" sort="Butzkueven, Helmut" uniqKey="Butzkueven H" first="Helmut" last="Butzkueven">Helmut Butzkueven</name><name sortKey="Jokubaitis, Vilija" sort="Jokubaitis, Vilija" uniqKey="Jokubaitis V" first="Vilija" last="Jokubaitis">Vilija Jokubaitis</name><name sortKey="Kalincik, Tomas" sort="Kalincik, Tomas" uniqKey="Kalincik T" first="Tomas" last="Kalincik">Tomas Kalincik</name><name sortKey="Lechner Scott, Jeannette" sort="Lechner Scott, Jeannette" uniqKey="Lechner Scott J" first="Jeannette" last="Lechner-Scott">Jeannette Lechner-Scott</name><name sortKey="Meyniel, Claire" sort="Meyniel, Claire" uniqKey="Meyniel C" first="Claire" last="Meyniel">Claire Meyniel</name></country><country name="Argentine"><noRegion><name sortKey="Rojas, Juan Ignacio" sort="Rojas, Juan Ignacio" uniqKey="Rojas J" first="Juan Ignacio" last="Rojas">Juan Ignacio Rojas</name></noRegion><name sortKey="Cristiano, Edgardo" sort="Cristiano, Edgardo" uniqKey="Cristiano E" first="Edgardo" last="Cristiano">Edgardo Cristiano</name><name sortKey="Fiol, Marcela" sort="Fiol, Marcela" uniqKey="Fiol M" first="Marcela" last="Fiol">Marcela Fiol</name></country><country name="Italie"><noRegion><name sortKey="Lugaresi, Alessandra" sort="Lugaresi, Alessandra" uniqKey="Lugaresi A" first="Alessandra" last="Lugaresi">Alessandra Lugaresi</name></noRegion><name sortKey="Iuliano, Gerardo" sort="Iuliano, Gerardo" uniqKey="Iuliano G" first="Gerardo" last="Iuliano">Gerardo Iuliano</name><name sortKey="Pucci, Eugenio" sort="Pucci, Eugenio" uniqKey="Pucci E" first="Eugenio" last="Pucci">Eugenio Pucci</name><name sortKey="Trojano, Maria" sort="Trojano, Maria" uniqKey="Trojano M" first="Maria" last="Trojano">Maria Trojano</name></country><country name="Espagne"><noRegion><name sortKey="Izquierdo, Guillermo" sort="Izquierdo, Guillermo" uniqKey="Izquierdo G" first="Guillermo" last="Izquierdo">Guillermo Izquierdo</name></noRegion><name sortKey="Oreja Guevara, Celia" sort="Oreja Guevara, Celia" uniqKey="Oreja Guevara C" first="Celia" last="Oreja-Guevara">Celia Oreja-Guevara</name></country><country name="Canada"><noRegion><name sortKey="Grand Maison, Francois" sort="Grand Maison, Francois" uniqKey="Grand Maison F" first="Francois" last="Grand'Maison">Francois Grand'Maison</name></noRegion><name sortKey="Duquette, Pierre" sort="Duquette, Pierre" uniqKey="Duquette P" first="Pierre" last="Duquette">Pierre Duquette</name><name sortKey="Grammond, Pierre" sort="Grammond, Pierre" uniqKey="Grammond P" first="Pierre" last="Grammond">Pierre Grammond</name><name sortKey="Moore, Fraser" sort="Moore, Fraser" uniqKey="Moore F" first="Fraser" last="Moore">Fraser Moore</name></country><country name="Turquie"><noRegion><name sortKey="Boz, Cavit" sort="Boz, Cavit" uniqKey="Boz C" first="Cavit" last="Boz">Cavit Boz</name></noRegion><name sortKey="Terzi, Murat" sort="Terzi, Murat" uniqKey="Terzi M" first="Murat" last="Terzi">Murat Terzi</name></country><country name="Koweït"><noRegion><name sortKey="Alroughani, Raed" sort="Alroughani, Raed" uniqKey="Alroughani R" first="Raed" last="Alroughani">Raed Alroughani</name></noRegion></country><country name="République tchèque"><region name="Bohême centrale"><name sortKey="Havrdova, Eva" sort="Havrdova, Eva" uniqKey="Havrdova E" first="Eva" last="Havrdova">Eva Havrdova</name></region><name sortKey="Horakova, Dana" sort="Horakova, Dana" uniqKey="Horakova D" first="Dana" last="Horakova">Dana Horakova</name></country><country name="Pays-Bas"><noRegion><name sortKey="Hupperts, Raymond" sort="Hupperts, Raymond" uniqKey="Hupperts R" first="Raymond" last="Hupperts">Raymond Hupperts</name></noRegion><name sortKey="Verheul, Freek" sort="Verheul, Freek" uniqKey="Verheul F" first="Freek" last="Verheul">Freek Verheul</name></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Van Pesch, Vincent" sort="Van Pesch, Vincent" uniqKey="Van Pesch V" first="Vincent" last="Van Pesch">Vincent Van Pesch</name></region></country><country name="Danemark"><noRegion><name sortKey="Petersen, Thor" sort="Petersen, Thor" uniqKey="Petersen T" first="Thor" last="Petersen">Thor Petersen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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